October 18, 2017 3 min read

Hyaluronic acid has been one of the latest buzzwords in the skincare industry. It has been called “the skincare star ingredient”, a “hydration miracle”, a “moisture magnet”, and even “the fountain of youth”. It’s clear that the general consensus is that hyaluronic acid is a must-have ingredient in any reputable anti-aging skincare product. But what exactly is hyaluronic acid? And why is it so beneficial for the skin? Keep reading below to learn the answers to these questions and more about today’s ingredient spotlight on hyaluronic acid.

What is hyaluronic acid?

Hyaluronic acid is a type of glycosaminoglycan (GAG), which is a long polysaccharide (sugar molecule) composed of disaccharides called amino sugars and uronic acid. GAGs are negatively charged and thus tend to attract positively charged sodium and potassium ions. In turn, this causes the GAGs to absorb and hold water. Therefore, GAGs play an important role in regulating the water and electrolyte balance of tissues. In fact,hyaluronic acid is the key molecule involved in skin moisture since it is capable of holdingup to 1,000 times its weight in water.


A drop of water creating a splash


In humans, hyaluronic acid is most abundant in the skin, accounting for50% of the body’s total content of hyaluronic acid. It can be found in the skin’s the extracellular matrix (ECM), along with other GAGs, growth factors, and structural proteins such as collagen and elastin. The predominant component of the skin ECM is hyaluronic acid. Additionally, hyaluronic acid isalso present in all tissues and fluids of the body, such as skeletal tissues, heart valves, the lung, the fluid surrounding the eyes, etc. Hyaluronic acid has many functions throughout the body, including hydration, lubrication of joints, wound healing, and providing the framework through which cells migrate.

Skincare benefits of hyaluronic acid

Did you know that youthful skin retains its turgor, resilience, and flexibility due to its high content of water? As the skin loses moisture due to both internal and external factors, it begins to show signs of aging, such as lines, wrinkles, sagging, and flaking skin. Since hyaluronic acid is the key molecule involved with skin moisture, it’s clear that a strong relationship exists between skin aging and levels of hyaluronic acid.


According to the scholarly journalDermatoEndocrinology, the most dramatic histochemical change observed in aging skin is the marked disappearance of hyaluronic acid in the epidermis. Hyaluronic acid has also been proven topossess a protective effect on collagen synthesis. Therefore, many anti-aging products contain hyaluronic acid in order to help reduce water loss in the skin and increase collagen production.  

A woman splashes water on her face

Hyaluronic acid can help naturally reduce signs of aging by decreasing epidermal water loss associated with sun exposure, low humidity, and other external factors associated with skin dryness. By using a high quality topical hyaluronic acid product, you can replenish your skin with the moisture needed to remain firm, smooth, and youthful.


Different forms of hyaluronic acid

Sodium hyaluronate, the water-soluble sodium salt form of hyaluronic acid, is commonly used instead of hyaluronic acid in skincare products due to itsgreater chemical stability.It is an effective humectant type moisturizer, which means it is able to draw in moisture from the environment and help the skin retain it.


Another form of hyaluronic acid that is found in skincare products is botanical hyaluronic acid.Botanical hyaluronic acid is ethically derived from a plantnative to India called Cassia Angustifolia. Seeds from this plant contain a high content of polysaccharides that mimic hyaluronic acid. When applied topicallybotanical hyaluronic acid penetrates the dermis to secure moisture, increase skin elasticity, and assist in tissue repair and protection. In fact, Cassia Angustifolia Seed Extract has beenclinically proven to deliver superior skin hydration benefits compared to hyaluronic acid!

A bunch of yellow flowers

Understanding the benefits of botanical hyaluronic acid, we have included this moisture-loving ingredient in several of our products here at PharmWerks. For example, you’ll find botanical hyaluronic acid in both of our scar treatment lines:Scargenix Scar Therapy (for any and all scars) andScargenix Stretch Mark Therapy (developed specifically for stretched scars). Botanical hyaluronic acid is included in our scar treatment products due to the role hyaluronic acid plays in rebuilding the skin’s ECM after an injury.


You’ll also find botanical hyaluronic acid in ourImmacuderm Radiance Restored Collection, a line of premium skin care products to erase wrinkles around the eyes and mouth, to reverse the aging process, and to bring back the radiance of youth. This collection contains theAgeless Facial Serum, theDaily Use Skin Hydrator, theEye Illuminating Gel, and theLuminosity Reviving Cream, all which contain the right amount of botanical hyaluronic acid to replenish your skin with moisture.


Now that you know all of the benefits of botanical hyaluronic acid, all you have to do is choose the product that is best for you!